Award
NIH Reporter #1F32GM161060-01A1
Elucidating the role of N-glycanase in glycoprotein activation, trafficking, and degradation
Recipient
Stanford University
Award Amount
$76,780.00
Ceiling
$76,780.00
Awarded
August 25, 2026
Identifier
1F32GM161060-01A1
The project will investigate NGLY1 substrates and cellular functions using chemical biology, proteomics, microscopy, and biochemical modeling, with the goal of better understanding NGLY1 deficiency and validating NGLY1 as a potential therapeutic target.
Description
Research project investigating how N-Glycanase 1 (NGLY1) affects glycoprotein trafficking, activity, and degradation, and its role in NGLY1 deficiency.