# NIH Reporter #1F32GM161060-01A1

Elucidating the role of N-glycanase in glycoprotein activation, trafficking, and degradation

**Recipient:** Stanford University

**Award Amount:** $76,780.00
**Ceiling:** $76,780.00

**Awarded:** August 25, 2026

**Identifier:** 1F32GM161060-01A1

The project will investigate NGLY1 substrates and cellular functions using chemical biology, proteomics, microscopy, and biochemical modeling, with the goal of better understanding NGLY1 deficiency and validating NGLY1 as a potential therapeutic target.

### Description

Research project investigating how N-Glycanase 1 (NGLY1) affects glycoprotein trafficking, activity, and degradation, and its role in NGLY1 deficiency.

[View original record](https://reporter.nih.gov/search/6baCKDp7ZEulW6R91k0BqA/project-details/11461519)