Award

NIH Reporter #5R01MH132740-04

A mechanistic trial of the neurobiology of extinction learning and intraparietal sulcus stimulation

Recipient

University of Pennsylvania

Award Amount

$762,151.00

Ceiling

$762,151.00

Awarded

October 29, 2026

Identifier

5R01MH132740-04

The University of Pennsylvania will conduct a randomized controlled study of 120 participants to examine the effects of intraparietal sulcus stimulation on arousal, extinction learning, and related neural mechanisms in people with PTSD.

Description

A clinical trial evaluating whether continuous theta burst stimulation of the intraparietal sulcus, combined with extinction training, reduces arousal and improves extinction learning retention among patients with PTSD.

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