# NIH Reporter #5R01MH132740-04

A mechanistic trial of the neurobiology of extinction learning and intraparietal sulcus stimulation

**Recipient:** University of Pennsylvania

**Award Amount:** $762,151.00
**Ceiling:** $762,151.00

**Awarded:** October 29, 2026

**Identifier:** 5R01MH132740-04

The University of Pennsylvania will conduct a randomized controlled study of 120 participants to examine the effects of intraparietal sulcus stimulation on arousal, extinction learning, and related neural mechanisms in people with PTSD.

### Description

A clinical trial evaluating whether continuous theta burst stimulation of the intraparietal sulcus, combined with extinction training, reduces arousal and improves extinction learning retention among patients with PTSD.

[View original record](https://reporter.nih.gov/search/a_XEnEpPR0i-06zXlbqcPw/project-details/11458471)