Award
NIH Reporter #5K08CA279499-04
Targeting regenerative reprogramming in colorectal cancer
Recipient
University of Texas MD Anderson Cancer Center
Award Amount
$292,594.00
Ceiling
$292,594.00
Awarded
August 20, 2026
Identifier
5K08CA279499-04
The project investigates preexisting cancer-cell states and epigenetic adaptations that enable therapy resistance in colorectal cancer. It will use lineage tracing, single-cell technologies, patient-derived organoids, and screening of chromatin regulators to identify and test potential treatments.
Description
NIH award supporting research into how colorectal cancer cells develop treatment resistance through regenerative reprogramming, and approaches to reverse these adaptations.