Award
NIH Reporter #1F31HL184619-01
Molecular mechanisms of muscle thin-filament length regulation
Recipient
University of Pennsylvania
Award Amount
$50,114.00
Ceiling
$50,114.00
Awarded
May 07, 2026
Identifier
1F31HL184619-01
The project studies the structural and functional roles of Lmod and SH3BGR in regulating thin-filament length in muscle, with the goal of understanding related myopathies.
Description
This project investigates how leiomodin (Lmod) and SH3BGR regulate thin-filament pointed-end length and dynamics, including their links to muscle diseases.