# NIH Reporter #1F31HL184619-01

Molecular mechanisms of muscle thin-filament length regulation

**Recipient:** University of Pennsylvania

**Award Amount:** $50,114.00
**Ceiling:** $50,114.00

**Awarded:** May 07, 2026

**Identifier:** 1F31HL184619-01

The project studies the structural and functional roles of Lmod and SH3BGR in regulating thin-filament length in muscle, with the goal of understanding related myopathies.

### Description

This project investigates how leiomodin (Lmod) and SH3BGR regulate thin-filament pointed-end length and dynamics, including their links to muscle diseases.

[View original record](https://reporter.nih.gov/search/J7l2tQ4hHkqRePwGq3m5kA/project-details/11314858)