Award
NIH Reporter #1F31CA314328-01
Therapeutic restoration of CUX1 in -7/del(7q) acute myeloid leukemia
Recipient
University of Chicago
Award Amount
$50,114.00
Ceiling
$50,114.00
Awarded
May 19, 2026
Identifier
1F31CA314328-01
The project aims to identify how SLC25A1 perturbation restores CUX1 levels and assess whether SLC25A1 inhibition combined with venetoclax could help treat high-risk myeloid neoplasms involving chromosome 7 loss.
Description
Research project investigating CUX1 regulation and the therapeutic potential of SLC25A1 inhibition, including in combination with venetoclax, for -7/del(7q) myeloid neoplasia.