# NIH Reporter #1F31CA314328-01

Therapeutic restoration of CUX1 in -7/del(7q) acute myeloid leukemia

**Recipient:** University of Chicago

**Award Amount:** $50,114.00
**Ceiling:** $50,114.00

**Awarded:** May 19, 2026

**Identifier:** 1F31CA314328-01

The project aims to identify how SLC25A1 perturbation restores CUX1 levels and assess whether SLC25A1 inhibition combined with venetoclax could help treat high-risk myeloid neoplasms involving chromosome 7 loss.

### Description

Research project investigating CUX1 regulation and the therapeutic potential of SLC25A1 inhibition, including in combination with venetoclax, for -7/del(7q) myeloid neoplasia.

[View original record](https://reporter.nih.gov/search/47CiHD0bJ0u2LtDABS0zbg/project-details/11390004)