Award
NIH Reporter #2R01HD104672-06
Proton-secreting epithelial cells as key modulators of epididymal mucosal immunity
Recipient
Massachusetts General Hospital, Boston, MA, United States
Award Amount
$643,333.00
Ceiling
$643,333.00
Awarded
September 11, 2026
Identifier
2R01HD104672-06
Research project funded by NICHD to study proton-secreting epithelial cells in the epididymis to improve male infertility treatments and develop male contraceptives.
Description
This project aims to advance treatments for male infertility and identify new targets for male contraception by studying the role of proton-secreting epithelial cells in the epididymis. The research focuses on understanding how these cells maintain immune privilege and regulate immune responses to protect sperm from autoimmunity and pathogens.