Award
NIH Reporter #1R61HD123436-01
Quantitative Assessment of Free Steroid Hormones to Characterize Endometrial Receptivity Towards Improving Pregnancy Outcomes in Frozen Embryo Transfer (FET) Cycles
Recipient
Brigham and Women's Hospital, Boston, MA, United States
Award Amount
$477,694.00
Ceiling
$477,694.00
Awarded
September 08, 2026
Identifier
1R61HD123436-01
Development of TruFERT™, a noninvasive diagnostic platform using AI to predict endometrial receptivity and improve pregnancy outcomes in frozen embryo transfer cycles.
Description
This project aims to reduce FET failure rates by developing a noninvasive, AI-driven diagnostic platform to assess endometrial receptivity and optimize transfer timing. The project will be conducted in two phases: R61 Phase to measure hormone concentrations and develop an AI model, and R33 Phase to validate the model and deploy a decision-support system integrated into electronic medical records.