# NIH Reporter #1R61HD123436-01

Quantitative Assessment of Free Steroid Hormones to Characterize Endometrial Receptivity Towards Improving Pregnancy Outcomes in Frozen Embryo Transfer (FET) Cycles

**Recipient:** Brigham and Women's Hospital, Boston, MA, United States

**Award Amount:** $477,694.00
**Ceiling:** $477,694.00

**Awarded:** September 08, 2026

**Identifier:** 1R61HD123436-01

Development of TruFERT™, a noninvasive diagnostic platform using AI to predict endometrial receptivity and improve pregnancy outcomes in frozen embryo transfer cycles.

### Description

This project aims to reduce FET failure rates by developing a noninvasive, AI-driven diagnostic platform to assess endometrial receptivity and optimize transfer timing. The project will be conducted in two phases: R61 Phase to measure hormone concentrations and develop an AI model, and R33 Phase to validate the model and deploy a decision-support system integrated into electronic medical records.

[View original record](https://reporter.nih.gov/search/0C83gI3MXki4-tEhFD4UKQ/project-details/11455938)