Award
NIH Reporter #1R21AG104396-01
An Overlooked Steroid Hormone as a Driver of Cognitive Resilience
Recipient
National Institute on Aging
Award Amount
$451,000.00
Ceiling
$451,000.00
Awarded
August 17, 2026
Identifier
1R21AG104396-01
This NIH award supports research on the steroid hormone ADIOL to understand its role in cognitive resilience and potential to reduce Alzheimer's disease risk.
Description
The project investigates a steroid hormone, ADIOL, as a regulator of cognitive capacity, with mechanistic studies in mice and correlative studies in humans. The project aims to uncover steroid-based mechanisms to enhance cognitive healthspan and reduce vulnerability to Alzheimer’s disease and related dementias.