Award

NIH Reporter #1F31AI197725-01

Defining MARCO as an Innate Checkpoint

Recipient

University of Massachusetts Medical School Worcester

Award Amount

$38,153.00

Ceiling

$38,153.00

Awarded

May 15, 2026

Identifier

1F31AI197725-01

The project investigates how MARCO regulates LPS detection and inflammatory cell death, including how interferons affect MARCO expression and whether MARCO deficiency increases susceptibility to sepsis.

Description

Research fellowship project studying the role and regulation of MARCO, a proposed LPS decoy receptor, and its effects on immune surveillance, inflammasome activation, and sepsis.

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