Award
NIH Reporter #2R35GM142505-06
Editing Acetylation and Protein Homeostasis
Recipient
University of Pennsylvania
Award Amount
$446,875.00
Ceiling
$446,875.00
Awarded
September 10, 2026
Identifier
2R35GM142505-06
This NIH grant funds research on protein homeostasis regulation via acetylation, aiming to develop chemical tools to manipulate protein acetylation and study ubiquitination, with potential therapeutic applications.
Description
The project aims to understand the general principles by which protein degradation can be controlled by protein acetylation and to develop chemical tools to manipulate the acetylation status of proteins, providing insights into fundamental biological processes and new therapeutic approaches for various diseases.