# NIH Reporter #2R35GM142505-06

Editing Acetylation and Protein Homeostasis

**Recipient:** University of Pennsylvania

**Award Amount:** $446,875.00
**Ceiling:** $446,875.00

**Awarded:** September 10, 2026

**Identifier:** 2R35GM142505-06

This NIH grant funds research on protein homeostasis regulation via acetylation, aiming to develop chemical tools to manipulate protein acetylation and study ubiquitination, with potential therapeutic applications.

### Description

The project aims to understand the general principles by which protein degradation can be controlled by protein acetylation and to develop chemical tools to manipulate the acetylation status of proteins, providing insights into fundamental biological processes and new therapeutic approaches for various diseases.

[View original record](https://reporter.nih.gov/search/0C83gI3MXki4-tEhFD4UKQ/project-details/11329140)