Award
NIH Reporter #1R01CA308971-01A1
Multimodal approach to decipher CIC::DUX4 sarcoma
Recipient
University of Minnesota
Award Amount
$548,075.00
Ceiling
$548,075.00
Awarded
September 17, 2026
Identifier
1R01CA308971-01A1
The project develops and uses mouse models to investigate how CIC::DUX4 drives sarcoma, examine interactions with the tumor immune environment, and test targeted P300/CBP inhibition.
Description
Research project to study CIC::DUX4 sarcoma using mouse models, investigate mechanisms of tumor transformation and immune evasion, and evaluate P300/CBP inhibition as a potential therapeutic approach.