Award
NIH Reporter #1R01GM169397-01
Integrating Language Models and Topology for Multi-Scale R-Loop Prediction
Recipient
University of California at Davis
Award Amount
$409,731.00
Ceiling
$409,731.00
Awarded
September 02, 2026
Identifier
1R01GM169397-01
Research to predict where R-loops form and how DNA topology shapes their structure, using laboratory experiments, mathematical modeling, and machine learning.
Description
The project develops a predictive, multi-scale quantitative framework combining experimental techniques with mathematical and machine-learning models to study R-loop formation, DNA topology, and three-dimensional structure.