Award
NIH Reporter #4UH3NS134619-03
Transcranial Electrical Stimulation in Stroke EaRly After onset Clinical Trial-2 (TESSERACT 2)
Recipient
University of California Los Angeles
Award Amount
$746,698.00
Ceiling
$746,698.00
Awarded
September 17, 2026
Identifier
4UH3NS134619-03
This award funds a clinical trial to test transcranial electrical stimulation as a novel treatment for acute ischemic stroke, aiming to optimize dosing for safety and efficacy.
Description
A multi-site, phase 2a, randomized, sham-controlled, dose-optimization study of high-definition (HD) C-tDCS as a neuroprotective and collateral enhancing treatment for acute ischemic stroke (AIS). The study aims to find an optimal dose that is safe and effective based on imaging biomarkers, using an adaptive Bayesian design with specific safety and efficacy endpoints.