# NIH Reporter #4UH3NS134619-03

Transcranial Electrical Stimulation in Stroke EaRly After onset Clinical Trial-2 (TESSERACT 2)

**Recipient:** University of California Los Angeles

**Award Amount:** $746,698.00
**Ceiling:** $746,698.00

**Awarded:** September 17, 2026

**Identifier:** 4UH3NS134619-03

This award funds a clinical trial to test transcranial electrical stimulation as a novel treatment for acute ischemic stroke, aiming to optimize dosing for safety and efficacy.

### Description

A multi-site, phase 2a, randomized, sham-controlled, dose-optimization study of high-definition (HD) C-tDCS as a neuroprotective and collateral enhancing treatment for acute ischemic stroke (AIS). The study aims to find an optimal dose that is safe and effective based on imaging biomarkers, using an adaptive Bayesian design with specific safety and efficacy endpoints.

[View original record](https://reporter.nih.gov/search/IgE1H2ioLUOz0qmA4MDg0Q/project-details/11416270)