Award
NIH Reporter #5R01AI186995-02
Molecular characterization and modeling efficient antibody effector function
Recipient
Dartmouth College
Award Amount
$442,024.00
Ceiling
$442,024.00
Awarded
December 05, 2025
Identifier
5R01AI186995-02
The project investigates how antigen, antibody, and effector-cell properties shape antibody effector functions, with the goal of developing quantitative models and design criteria for antibody therapeutics.
Description
Research project to experimentally characterize antibody features that trigger potent antibody-dependent cellular cytotoxicity (ADCC) and phagocytosis, and to establish rules guiding antibody immunotherapies.