Award
NIH Reporter #1F32EY037536-01A1
Scalable Prime Editor Evolution for Correction of Inherited Retinal Diseases
Recipient
University of California-Irvine
Award Amount
$79,480.00
Ceiling
$79,480.00
Awarded
April 03, 2026
Identifier
1F32EY037536-01A1
The National Eye Institute awarded funding to support research and training focused on evolving more effective prime editors for inherited retinal disease targets.
Description
Project to use the OrthoRep system to evolve prime editors for improved editing of clinically relevant sequences associated with inherited retinal diseases, including mutations in MERTK and C1QTNF5, and assess their efficiency and specificity in cell and animal models.