# NIH Reporter #1F32EY037536-01A1

Scalable Prime Editor Evolution for Correction of Inherited Retinal Diseases

**Recipient:** University of California-Irvine

**Award Amount:** $79,480.00
**Ceiling:** $79,480.00

**Awarded:** April 03, 2026

**Identifier:** 1F32EY037536-01A1

The National Eye Institute awarded funding to support research and training focused on evolving more effective prime editors for inherited retinal disease targets.

### Description

Project to use the OrthoRep system to evolve prime editors for improved editing of clinically relevant sequences associated with inherited retinal diseases, including mutations in MERTK and C1QTNF5, and assess their efficiency and specificity in cell and animal models.

[View original record](https://reporter.nih.gov/search/47CiHD0bJ0u2LtDABS0zbg/project-details/11318797)