Award
NIH Reporter #1U19AI201306-01
Expression-Based Vaccine
Recipient
Johns Hopkins University
Award Amount
$352,452.00
Ceiling
$352,452.00
Awarded
September 17, 2026
Identifier
1U19AI201306-01
NIH-funded research at Johns Hopkins University to develop and evaluate an HCV vaccine using designed antigens to elicit broad antibody and T-cell responses.
Description
Project to design an expression-based hepatitis C virus vaccine intended to induce broadly neutralizing antibodies and genotype-cross-reactive T-cell responses. The project will map antibody targets, develop and test designed vaccine antigens, and compare immune responses in rhesus macaques and humans with spontaneous HCV clearance.