Award
NIH Reporter #2R56NS114289-06A1
Determining mechanisms regulating TDP-43 pathology, the link between aggregation and dysfunction
Recipient
Saint Louis University
Award Amount
$568,590.00
Ceiling
$568,590.00
Awarded
September 17, 2026
Identifier
2R56NS114289-06A1
Funding supports research into mechanisms linking TDP-43 aggregation, nuclear depletion, and dysfunction, with the goal of identifying disease mechanisms and potential therapeutic and diagnostic strategies.
Description
NIH project studying how TDP-43 aggregation causes loss of function and contributes to neurodegenerative disorders, including ALS and Frontotemporal Dementia.