Award
NIH Reporter #5F31AG091981-02
Genetic and Environmental Sources of Heterogeneity in Alzheimer's Disease: A Pathway Specific Approach
Recipient
University of Pennsylvania
Award Amount
$50,114.00
Ceiling
$50,114.00
Awarded
August 28, 2026
Identifier
5F31AG091981-02
The project will study genetic and environmental sources of heterogeneity in Alzheimer's disease by developing and comparing pathway-specific polygenic risk scores and assessing how their effects vary with fine particulate matter exposure.
Description
Project to explore methods for constructing pathway-specific polygenic risk scores and investigate interactions between pathway-specific genetic risk factors and fine particulate matter exposure in relation to dementia risk.