Award
NIH Reporter #5F31HL179994-02
The role of sex chromosomes in neonatal hyperoxic lung injury
Recipient
University of Pennsylvania
Award Amount
$50,114.00
Ceiling
$50,114.00
Awarded
August 06, 2026
Identifier
5F31HL179994-02
The project investigates how sex chromosome dosage and endothelial Kdm6a affect neonatal lung injury caused by hyperoxia, aiming to explain sex differences in bronchopulmonary dysplasia and identify potential therapeutic targets.
Description
Research on the role of sex chromosome dosage and the X-linked gene Kdm6a in sex-specific outcomes in a mouse model of bronchopulmonary dysplasia and neonatal hyperoxic lung injury.