# NIH Reporter #5F31HL179994-02

The role of sex chromosomes in neonatal hyperoxic lung injury

**Recipient:** University of Pennsylvania

**Award Amount:** $50,114.00
**Ceiling:** $50,114.00

**Awarded:** August 06, 2026

**Identifier:** 5F31HL179994-02

The project investigates how sex chromosome dosage and endothelial Kdm6a affect neonatal lung injury caused by hyperoxia, aiming to explain sex differences in bronchopulmonary dysplasia and identify potential therapeutic targets.

### Description

Research on the role of sex chromosome dosage and the X-linked gene Kdm6a in sex-specific outcomes in a mouse model of bronchopulmonary dysplasia and neonatal hyperoxic lung injury.

[View original record](https://reporter.nih.gov/search/J7l2tQ4hHkqRePwGq3m5kA/project-details/11505881)