Award
NIH Reporter #1R43HL178322-01A1
A cardiopulmonary unit-on-a-chip to investigate the pathophysiology and develop targeted treatments for right ventricular hypertrophy caused by pulmonary arterial hypertension
Recipient
Adnan Akif
Award Amount
$227,639.00
Ceiling
$227,639.00
Awarded
August 31, 2026
Identifier
1R43HL178322-01A1
This NIH-funded project aims to create an innovative 'organ-on-a-chip' model to better understand and develop treatments for PAH-related RVH, with a focus on sex differences and personalized medicine.
Description
This project involves developing a microfluidic 'cardiopulmonary-unit-on-a-chip' to model right ventricular hypertrophy (RVH) caused by pulmonary arterial hypertension (PAH). The model aims to incorporate features such as rhythmic contraction, blood flow-induced pressure, and electrical stimulation, and will be used to study sex differences and test medications.