Award
NIH Reporter #2R35GM142588-06
Biophysical mechanism and synthetic engineering of optically controlled Ca2+-powered supramolecular engines
Recipient
University of Colorado
Award Amount
$2,165,625.00
Ceiling
$2,165,625.00
Awarded
August 13, 2026
Identifier
2R35GM142588-06
The project studies the mechanisms behind calcium-triggered contractions in centrin/Sfi1 protein assemblies and aims to build synthetic, AI-controlled myonemes for programmable force generation.
Description
NIH-funded research investigating how calcium-responsive centrin/Sfi1 myonemes generate mechanical force and engineering synthetic myonemes with programmable, light-controlled actuation.