Award
NIH Reporter #5R01DA054526-05
Modeling HIV Microglia-Associated Infection and Inflammation in a Chimeric Mouse Brain
Recipient
Icahn School of Medicine at Mount Sinai
Award Amount
$749,597.00
Ceiling
$749,597.00
Awarded
June 23, 2025
Identifier
5R01DA054526-05
NIH-funded research investigating HIV latency, infection, and neuroinflammation in human microglia within a chimeric mouse brain, and evaluating therapies that may affect infection and inflammation.
Description
The project studies HIV infection and persistence in human microglia residing in a mouse brain, including microglial inflammation and effects of antiretroviral and cannabinoid receptor 2 agonist treatments.