Award
NIH Reporter #5R01HL163857-04
Premature aging disorders, metabolites, and atherosclerosis
Recipient
UNIVERSITY OF TX MD ANDERSON CAN CTR
Award Amount
$691,393.00
Ceiling
$691,393.00
Awarded
February 16, 2026
Identifier
5R01HL163857-04
The project investigates molecular mechanisms linking premature aging-related vascular diseases to atherosclerosis, focusing on metabolite pathways and the PKCζ-TOP2β and PARP pathways.
Description
NIH research project examining how premature senescence-triggered vascular diseases and Hutchinson-Gilford progeria syndrome affect metabolites, endothelial cell dysfunction, and atherosclerosis.