Award
NIH Reporter #11263857
Research Project 2: Biomaterial-driven CAR T cell generation for treatment of GBM
Recipient
UNIV OF NORTH CAROLINA CHAPEL HILL
Award Amount
$370,392.00
Ceiling
$370,392.00
Awarded
March 05, 2026
Identifier
11263857
This award funds a research project by the University of North Carolina Chapel Hill to develop biomaterial-driven CAR T cell therapy for glioblastoma multiforme (GBM). The project includes manufacturing, in vivo testing, and safety evaluation over approximately 5 years with a total award amount of $370,392.
Description
The project aims to develop a platform for CAR T cell manufacturing using a biomaterial scaffold. The project involves in vivo generation of CAR T cells, phenotypic and functional characterization, and safety testing. The project emphasizes innovation in GBM treatment and expanding patient access to CAR T therapy.