Award
NIH Reporter #1U01CA307238-01A1
Metabolism of dietary fatty acids promotes castration resistance in prostate cancer
Recipient
University of Georgia, Athens, GA
Award Amount
$587,112.00
Ceiling
$587,112.00
Awarded
September 10, 2026
Identifier
1U01CA307238-01A1
This NIH-funded project studies the role of dietary fatty acid metabolism in promoting castration resistance in prostate cancer, using various experimental models to uncover molecular mechanisms and potential therapeutic targets.
Description
The project investigates how high-fatty-acid diets promote prostate cancer resistance to castration. The study involves designing fatty acid-enriched diets, in vitro and in vivo models, including transgenic mice and patient-derived xenograft models. The goal is to understand fatty acid metabolism's role in prostate cancer progression and resistance to therapy.