Award
NIH Reporter #1R61NS146000-01A1
Generation of a CCL2-CGRP Bispecific Neutralizing Antibody to Treat Chronic Post-Traumatic Headache
Recipient
Washington University
Award Amount
$816,375.00
Ceiling
$816,375.00
Awarded
September 17, 2026
Identifier
1R61NS146000-01A1
NIH-funded research to develop and evaluate a CCL2-CGRP bispecific antibody for chronic post-traumatic headache.
Description
Develop a bispecific neutralizing antibody that simultaneously targets CCL2 and CGRP as a potential non-opioid treatment for chronic post-traumatic headache. The project includes antibody generation, humanization and engineering, and preclinical testing.