Award
NIH Reporter #5R01MH134893-04
Mitochondrial influences on blood brain barrier function and neuropsychiatric illness
Recipient
University of Pennsylvania
Award Amount
$674,894.00
Ceiling
$674,894.00
Awarded
October 28, 2026
Identifier
5R01MH134893-04
NIH-funded research on mitochondrial dysfunction and blood-brain barrier impairment related to neuropsychiatric illness, including potential therapeutic approaches.
Description
The project examines how mitochondrial energetic compromise interacts with structural weaknesses in the blood-brain barrier in 22q11.2 deletion syndrome, and whether interventions that improve mitochondrial energetics can improve barrier function.