Award
NIH Reporter #4R01AG058273-03
Neuroinflammatory Mechanisms of Vascular Cognitive Impairment
Recipient
Oregon Health & Science University
Award Amount
$536,116.00
Ceiling
$536,116.00
Awarded
September 15, 2026
Identifier
4R01AG058273-03
Research project funded to study neuroinflammatory mechanisms contributing to vascular cognitive impairment, focusing on metabolic syndrome and immune cell infiltration using mouse models.
Description
This project investigates the role of metabolic syndrome, endothelial soluble epoxide hydrolase (sEH), and immune cell infiltration in cognitive decline, using mouse models and advanced molecular techniques. It aims to elucidate novel mechanisms of age-dependent immune infiltration and neuroinflammation in vascular cognitive impairment, with potential for developing targeted therapies.