Award
NIH Reporter #5F30EB035471-02
Outer sphere tuning of a Eu(II)-containing contrast agent for imaging hypoxia via MRI
Recipient
Wayne State University
Award Amount
$44,619.00
Ceiling
$44,619.00
Awarded
March 04, 2026
Identifier
5F30EB035471-02
Wayne State University received NIH funding for research to improve the persistence of a europium-based MRI contrast agent, with the goal of enabling broader imaging of hypoxic regions.
Description
Research project investigating how to increase the persistence of Eu(II)-containing contrast agents in oxygenated environments to support systemic delivery and ratiometric imaging of hypoxia. The work examines oxygen solubility in perfluorocarbon nanoemulsions, gas diffusion effects, and nanoparticle size.