# NIH Reporter #5F30EB035471-02

Outer sphere tuning of a Eu(II)-containing contrast agent for imaging hypoxia via MRI

**Recipient:** Wayne State University

**Award Amount:** $44,619.00
**Ceiling:** $44,619.00

**Awarded:** March 04, 2026

**Identifier:** 5F30EB035471-02

Wayne State University received NIH funding for research to improve the persistence of a europium-based MRI contrast agent, with the goal of enabling broader imaging of hypoxic regions.

### Description

Research project investigating how to increase the persistence of Eu(II)-containing contrast agents in oxygenated environments to support systemic delivery and ratiometric imaging of hypoxia. The work examines oxygen solubility in perfluorocarbon nanoemulsions, gas diffusion effects, and nanoparticle size.

[View original record](https://reporter.nih.gov/search/0ftClcwKYUOEq8QKPKx2lA/project-details/11241105)