Award
NIH Reporter #5K23HD114892-02
Syphilis in pregnancy: placental histopathology and transcriptomic linkage to outcomes
Recipient
UT Southwestern Medical Center
Award Amount
$167,383.00
Ceiling
$167,383.00
Awarded
June 26, 2026
Identifier
5K23HD114892-02
NIH K23 career development award supporting research and training to investigate how syphilis and its treatment affect placental biology and neonatal outcomes, including preterm birth and congenital syphilis.
Description
The project will characterize Treponema pallidum-driven histopathologic and molecular changes at the maternal-placental-fetal immune interface and link maternal disease and treatment timing, treponemal burden, placental histopathology, and transcriptome profiles with preterm birth and congenital syphilis outcomes.