Award
NIH Reporter #1K99AI199380-01
Defining CD4+ T Cells Driving Protection and Susceptibility in Helminth Reinfection
Recipient
UT Southwestern Medical Center
Award Amount
$192,369.00
Ceiling
$192,369.00
Awarded
September 01, 2026
Identifier
1K99AI199380-01
The project investigates immune mechanisms underlying protection and persistent susceptibility to hookworm reinfection, with the goal of informing prevention, diagnosis, and treatment of parasitic and inflammatory diseases.
Description
K99/R00 research project studying CD4+ T-cell populations involved in protection against hookworm and how chronic infection alters their composition and function, using a rodent model and blood cells from adults with hookworm infection.