Award
NIH Reporter #1F31CA318731-01
LARP1-Driven Control of Ribosomal Biogenesis Alters Translation in CAR T cells
Recipient
University of Pennsylvania
Award Amount
$50,114.00
Ceiling
$50,114.00
Awarded
July 29, 2026
Identifier
1F31CA318731-01
The project studies LARP1’s role in controlling ribosomal biogenesis and translation in CAR T cells, and evaluates whether deleting LARP1 can improve CAR T cell persistence and antitumor activity.
Description
Research project investigating how the RNA-binding protein LARP1 regulates ribosomal biogenesis, translation, CAR T cell persistence, and antitumor activity.