Award
NIH Reporter #6F31HD114406-04
AAV gene therapy to restore fertility in mammalian Sertoli cell dysfunction models
Recipient
University of Pittsburgh at Pittsburgh
Award Amount
$50,114.00
Ceiling
$50,114.00
Awarded
August 27, 2026
Identifier
6F31HD114406-04
NIH grant funding research into AAV gene therapy as a potential treatment for infertility caused by Sertoli cell dysfunction.
Description
Project to test the feasibility and safety of AAV-mediated Sertoli cell gene therapy to restore fertility in mammalian models of Sertoli cell dysfunction, including evaluating the risk of germline modification and identifying AAV serotypes with Sertoli cell-specific infection in human testicular tissue.