Award
NIH Reporter #5P01CA163227-12
Functional Interplay Between PARP, AR and DNA Damage
Recipient
Beth Israel Deaconess Medical Center
Award Amount
$812,190.00
Ceiling
$812,190.00
Awarded
September 16, 2026
Identifier
5P01CA163227-12
NIH-funded research examining how PARP, androgen receptor signaling, BRCA1/BRCA2, and DNA damage interact in prostate cancer, with the goal of informing treatment strategies involving PARP inhibitors and AR-targeted therapies.
Description
Project to elucidate the functional interplay between androgen receptor signaling, PARP genes and inhibitors, BRCA1 and BRCA2, and DNA damage to develop improved strategies for treating aggressive prostate cancer.