Award

NIH Reporter #2R01AG052550-06A1

PET Imaging of Neuroinflammation in Genetic Alzheimer's Disease

Recipient

Washington University

Award Amount

$653,052.00

Ceiling

$653,052.00

Awarded

September 17, 2026

Identifier

2R01AG052550-06A1

Washington University received NIH funding for a five-year study using PET imaging and inflammatory biomarkers to investigate neuroinflammation in genetic Alzheimer's disease and Down syndrome.

Description

The project studies neuroinflammation in genetic Alzheimer's disease and Down syndrome using [11C]-CS1P1 PET imaging and blood and biofluid measures. It plans to longitudinally scan 125 participants over five years to examine how neuroinflammation relates to amyloid and tau accumulation.

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