# NIH Reporter #2R01AG052550-06A1

PET Imaging of Neuroinflammation in Genetic Alzheimer's Disease

**Recipient:** Washington University

**Award Amount:** $653,052.00
**Ceiling:** $653,052.00

**Awarded:** September 17, 2026

**Identifier:** 2R01AG052550-06A1

Washington University received NIH funding for a five-year study using PET imaging and inflammatory biomarkers to investigate neuroinflammation in genetic Alzheimer's disease and Down syndrome.

### Description

The project studies neuroinflammation in genetic Alzheimer's disease and Down syndrome using [11C]-CS1P1 PET imaging and blood and biofluid measures. It plans to longitudinally scan 125 participants over five years to examine how neuroinflammation relates to amyloid and tau accumulation.

[View original record](https://reporter.nih.gov/search/J7l2tQ4hHkqRePwGq3m5kA/project-details/11450739)