Award
NIH Reporter #5IK2CX002593-02
A lipid signaling network through stearoyl Co-A desaturase regulates hepatocellular carcinogenesis through YAP/TAZ activity
Recipient
Not specified
Awarded
September 18, 2026
Identifier
5IK2CX002593-02
Research project awarded by Veterans Affairs to study lipid signaling and its role in liver cancer development, focusing on YAP/TAZ activity and potential chemoprevention in Veterans.
Description
This project focuses on studying the effects of lipid pathways, including statins, on the YAP/TAZ oncogenic pathway in hepatocellular carcinoma, with aims to delineate mechanisms of lipids in HCC and explore chemopreventive strategies in Veterans with NAFLD-HCC.