# NIH Reporter #5IK2CX002593-02

A lipid signaling network through stearoyl Co-A desaturase regulates hepatocellular carcinogenesis through YAP/TAZ activity

**Recipient:** Not specified

**Awarded:** September 18, 2026

**Identifier:** 5IK2CX002593-02

Research project awarded by Veterans Affairs to study lipid signaling and its role in liver cancer development, focusing on YAP/TAZ activity and potential chemoprevention in Veterans.

### Description

This project focuses on studying the effects of lipid pathways, including statins, on the YAP/TAZ oncogenic pathway in hepatocellular carcinoma, with aims to delineate mechanisms of lipids in HCC and explore chemopreventive strategies in Veterans with NAFLD-HCC.

[View original record](https://reporter.nih.gov/search/IgE1H2ioLUOz0qmA4MDg0Q/project-details/11051158)