# DOE and NIH Build Biological AI Infrastructure

On October 7, 2026, NIH announced a DOE–NIH–Biohub MOU to organize and standardize biomedical datasets for predictive models of human biology under NIH’s Bio Genesis Mission. DOE plans to invest more than $500 million and Biohub $500 million over five years, combining DOE laboratory computing and research capabilities, NIH data and resources, and Biohub technology. The initiative points to potential future needs in biomedical data engineering, data standardization, research infrastructure, and high-throughput cell measurement, but the announcement identifies no outside solicitation or contract award. Separately, DHS Science and Technology Directorate is offering up to $999,990 through a biothreat-detection prize competition, with submissions due **October 14, 2026 (5 days remaining)**.

- The MOU signals a large-scale federal research and infrastructure effort, but the stated investments are not identified as procurements available to outside suppliers. Companies can position relevant capabilities in biomedical data management, standardization, computing, and cell measurement for potential future needs.
- The DHS prize competition is a near-term, distinct opportunity for teams developing algorithms to detect biological threats in environmental genetic data. Eligible applicants should use the competition information to assess fit and submit by October 14.
- Procurement teams should distinguish the announced research collaboration and its planned investments from competed contract opportunities; no solicitation, contract value for outside suppliers, or procurement contact is provided for the MOU.

**Jurisdictions:** federal
**Industries:** Healthcare, Information Technology
**Topics:** Artificial Intelligence, Digital Infrastructure, Grants & Funding
**Published:** October 08, 2026

### Government Entities
- National Institutes of Health (NIH)
- U.S. Department of Energy (DOE)
- Department of Homeland Security Science and Technology Directorate (DHS S&T)

### Vendors
- Biohub (MOU participant contributing technology and $500 million over five years)

### Key Quotes
> It will require coordinated data generation efforts at a national and international scale, which is why these partners are coming together.
> — Alex Rives, Biohub Head of Science

### Sources
- [DOE, NIH, Biohub Sign Pact on Biology Super Intelligence](https://www.executivegov.com/articles/doe-nih-biohub-super-intelligence-biology-agreement) - ExecutiveGov
- [NIH joins effort to build SI-ready data for predictive models of human biology  | National Institutes of Health (NIH)](https://www.nih.gov/news-events/news-releases/nih-joins-effort-build-si-ready-data-predictive-models-human-biology) - NIH