# Simpler Grants.gov #RFA-DK-28-314

NIH U54 Cooperative Research Centers for Urology

**Buyer:** National Institutes of Health
**Posted:** November 03, 2026
**Respond By:** February 01, 2027
**Identifier:** RFA-DK-28-314
**NAICS:** 541714, 541715

NIH is seeking research centers to advance multidisciplinary research on non-cancer genitourinary diseases and disorders.
- **Government buyer:** U.S. Department of Health and Human Services, National Institutes of Health (NIH), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK).
- **Opportunity:** George M. O’Brien Urology Cooperative Research Centers program, funded through U54 cooperative agreements.
- **Requested services:** Support multidisciplinary basic, translational, and clinical research, with each center serving as a resource for the broader urology research community.
  - Each center must have an Administrative Core and at least two Research Projects; three Research Projects are required if no Biomedical Research Core is proposed.
  - Biomedical Research Core(s) are optional, and clinical trials are optional.
- **Funding and duration:** Approximately $5.2 million in total costs is planned, with five awards anticipated. Budgets are expected to be approximately $750,000 in direct costs per year; projects may run for up to five years. Cost sharing is not required.
- **OEMs and vendors:** None identified.

### Description

This funding opportunity supports continuation of the NIDDK George M. O’Brien Urology Cooperative Research Centers (U54). The centers foster multidisciplinary research through collaborations within and outside the centers and serve as a national resource for the urology research community. The funding instrument is a cooperative agreement, with approximately $5.2 million in total costs intended for fiscal year 2027 and application budgets expected to be approximately $750,000 in direct costs per year. The maximum project period is five years, and cost sharing or matching is not required.

[View original listing](https://simpler.grants.gov/opportunity/360551)